The Global Emergency of Novel Coronavirus (SARS-CoV-2): An Update of the Current Status and Forecasting
Hozhabri, Hossein1; Piceci Sparascio, Francesca1,2; De Luca, Alessandro2; Sohrabi, Hamidreza3; Mousavifar, Leila4; Roy, Rene4; Scribano, Daniela1,5; Ambrosi, Cecilia6; Sarshar, Meysam1,7,8
2020-08
发表期刊INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
EISSN1660-4601
摘要Over the past two decades, there have been two major outbreaks where the crossover of animalBetacoronavirusesto humans has resulted in severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). In December 2019, a global public health concern started with the emergence of a new strain of coronavirus (SARS-CoV-2 or 2019 novel coronavirus, 2019-nCoV) which has rapidly spread all over the world from its origin in Wuhan, China. SARS-CoV-2 belongs to theBetacoronavirusgenus, which includes human SARS-CoV, MERS and two other human coronaviruses (HCoVs), HCoV-OC43 and HCoV-HKU1. The fatality rate of SARS-CoV-2 is lower than the two previous coronavirus epidemics, but it is faster spreading and the large number of infected people with severe viral pneumonia and respiratory illness, showed SARS-CoV-2 to be highly contagious. Based on the current published evidence, herein we summarize the origin, genetics, epidemiology, clinical manifestations, preventions, diagnosis and up to date treatments of SARS-CoV-2 infections in comparison with those caused by SARS-CoV and MERS-CoV. Moreover, the possible impact of weather conditions on the transmission of SARS-CoV-2 is also discussed. Therefore, the aim of the present review is to reconsider the two previous pandemics and provide a reference for future studies as well as therapeutic approaches.
关键词SARS-CoV-2 epidemiology transmission temperature and humidity COVID-19 pneumonia diagnosis ACE2 inhibitors therapeutics strategies
DOI10.3390/ijerph17165648
WOS关键词RESPIRATORY SYNDROME CORONAVIRUS ; MESENCHYMAL STEM-CELLS ; SARS-CORONAVIRUS ; SPIKE PROTEIN ; STROMAL CELLS ; GENOMIC CHARACTERIZATION ; HEMAGGLUTININ-ESTERASE ; TRANSMISSION DYNAMICS ; CONVALESCENT PLASMA ; ACE2 RECEPTOR
WOS研究方向Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
WOS类目Environmental Sciences ; Public, Environmental & Occupational Health
出版者MDPI
引用统计
文献类型期刊论文
专题新冠肺炎
循证社会科学证据集成
作者单位1.Sapienza Univ Rome;
2.Fdn IRCCS Casa Sollievo Sofferenza;
3.Univ Turin;
4.Univ Quebec;
5.Dani Di Gio Fdn Onlus;
6.San Raffaele Roma Open Univ;
7.Bambino Gesu Pediat Hosp;
8.Pasteur Inst Iran
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Hozhabri, Hossein,Piceci Sparascio, Francesca,De Luca, Alessandro,et al. The Global Emergency of Novel Coronavirus (SARS-CoV-2): An Update of the Current Status and Forecasting[J]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH,2020.
APA Hozhabri, Hossein.,Piceci Sparascio, Francesca.,De Luca, Alessandro.,Sohrabi, Hamidreza.,Mousavifar, Leila.,...&Sarshar, Meysam.(2020).The Global Emergency of Novel Coronavirus (SARS-CoV-2): An Update of the Current Status and Forecasting.INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH.
MLA Hozhabri, Hossein,et al."The Global Emergency of Novel Coronavirus (SARS-CoV-2): An Update of the Current Status and Forecasting".INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020).
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