Risk factors for predicting mortality in elderly patients with COVID-19: A review of clinical data in China

doi:10.1016/j.mad.2020.111255

	Risk factors for predicting mortality in elderly patients with COVID-19: A review of clinical data in China
	Leung, Char
	2020-06
发表期刊	MECHANISMS OF AGEING AND DEVELOPMENT
ISSN	0047-6374
EISSN	1872-6216
摘要	While elderly patients are at high risk of fatality, research concerning COVID-19 has largely been done on clarifying the clinical features. As such, the present work aims to identify risk factors for mortality in elderly patients with COVID-19. Given that single-centre studies are less likely informative as elderly remains a minority in the total Chinese population, the present study reviewed the clinical data of geriatric COVID-19 patients gathered from different sources in the public domain. Based on the data of 154 individuals from 26 provinces, age remained a key mortality risk factor among geriatric patients of different ages. While dyspnoea and chest pain/discomfort were more commonly seen in deceased patients as they represented severe pneumonia, fever was more prominent in surviving patients. This was likely due to the lower baseline body temperature observed in elderly which translated to a lower maximum temperature of fever. However, lowering the threshold temperature for fever is not recommended in surveillance. Instead, baseline body temperature measured on a regular basis should be used to define the threshold temperature for fever. Against mixed results, more research should be done on identifying comorbidities associated with mortality in geriatric patients.
关键词	COVID-19 Mortality Risk factors Geriatric patients Elderly
DOI	10.1016/j.mad.2020.111255
WOS关键词	BODY-TEMPERATURE ; PREVALENCE ; FEVER
WOS研究方向	Cell Biology ; Geriatrics & Gerontology
WOS类目	Cell Biology ; Geriatrics & Gerontology
出版者	ELSEVIER IRELAND LTD
引用统计
文献类型	期刊论文
专题	新冠肺炎循证社会科学证据集成
作者单位	Deakin Univ
推荐引用方式 GB/T 7714	Leung, Char. Risk factors for predicting mortality in elderly patients with COVID-19: A review of clinical data in China[J]. MECHANISMS OF AGEING AND DEVELOPMENT,2020.
APA	Leung, Char.(2020).Risk factors for predicting mortality in elderly patients with COVID-19: A review of clinical data in China.MECHANISMS OF AGEING AND DEVELOPMENT.
MLA	Leung, Char."Risk factors for predicting mortality in elderly patients with COVID-19: A review of clinical data in China".MECHANISMS OF AGEING AND DEVELOPMENT (2020).