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Impact of climate and public health interventions on the COVID-19 pandemic: a prospective cohort study | |
Juni, Peter1,2; Rothenbuhler, Martina1,3; Bobos, Pavlos1,4; Thorpe, Kevin E.1,2; da Costa, Bruno R.1,5; Slutsky, Arthur S.1,2; Fisman, David N.2; Gesink, Dionne2 | |
2020-05 | |
发表期刊 | CANADIAN MEDICAL ASSOCIATION JOURNAL
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ISSN | 0820-3946 |
EISSN | 1488-2329 |
摘要 | BACKGROUND: It is unclear whether seasonal changes, school closures or other public health interventions will result in a slowdown of the current coronavirus disease 2019 (COVID-19) pandemic. We aimed to determine whether epidemic growth is globally associated with climate or public health interventions intended to reduce transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). METHODS: We performed a prospective cohort study of all 144 geopolitical areas worldwide (375 609 cases) with at least 10 COVID-19 cases and local transmission by Mar. 20, 2020, excluding China, South Korea, Iran and Italy. Using weighted random-effects regression, we determined the association between epidemic growth (expressed as ratios of rate ratios [RRR] comparing cumulative counts of COVID-19 cases on Mar. 27, 2020, with cumulative counts on Mar. 20, 2020) and latitude, temperature, humidity, school closures, restrictions of mass gatherings, and measures of social distancing during an exposure period 14 days previously (Mar. 7 to 13, 2020). RESULTS: In univariate analyses, there were no associations of epidemic growth with latitude and temperature, but weak negative associations with relative humidity (RRR per 10% 0.91, 95% confidence interval [CI] 0.85-0.96) and absolute humidity (RRR per 5 g/m(3) 0.92, 95% CI 0.85-0.99). Strong associations were found for restrictions of mass gatherings (RRR 0.65, 95% CI 0.53-0.79), school closures (RRR 0.63, 95% CI 0.52-0.78) and measures of social distancing (RRR 0.62, 95% CI 0.45-0.85). In a multivariable model, there was a strong association with the number of implemented public health interventions (p for trend = 0.001), whereas the association with absolute humidity was no longer significant. INTERPRETATION: Epidemic growth of COVID-19 was not associated with latitude and temperature, but may be associated weakly with relative or absolute humidity. Conversely, public health interventions were strongly associated with reduced epidemic growth. |
DOI | 10.1503/cmaj.200920 |
WOS关键词 | SCHOOL CLOSURE ; INFLUENZA ; REGRESSION |
WOS研究方向 | General & Internal Medicine |
WOS类目 | Medicine, General & Internal |
出版者 | CMA-CANADIAN MEDICAL ASSOC |
引用统计 | |
文献类型 | 期刊论文 |
专题 | 新冠肺炎 循证社会科学证据集成 |
作者单位 | 1.St Michaels Hosp; 2.Univ Toronto; 3.Ava AG; 4.Western Univ; 5.Univ Bern |
推荐引用方式 GB/T 7714 | Juni, Peter,Rothenbuhler, Martina,Bobos, Pavlos,et al. Impact of climate and public health interventions on the COVID-19 pandemic: a prospective cohort study[J]. CANADIAN MEDICAL ASSOCIATION JOURNAL,2020. |
APA | Juni, Peter.,Rothenbuhler, Martina.,Bobos, Pavlos.,Thorpe, Kevin E..,da Costa, Bruno R..,...&Gesink, Dionne.(2020).Impact of climate and public health interventions on the COVID-19 pandemic: a prospective cohort study.CANADIAN MEDICAL ASSOCIATION JOURNAL. |
MLA | Juni, Peter,et al."Impact of climate and public health interventions on the COVID-19 pandemic: a prospective cohort study".CANADIAN MEDICAL ASSOCIATION JOURNAL (2020). |
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